The COVID-19 pandemic has radically changed living conditions globally, from the mundanities of everyday experience to our understanding of individual behavioral ethics. This volume—conceived as a “minimal encyclopedia”—offers reflections on emerging sensibilities and fields of action based on creative responses to human, cultural, and environmental challenges. It is a collection of interviews and essays written by distinguished interpreters of the present. Each piece takes its cue from a keyword starting with a different letter of the alphabet, then reflects on how contemporary society is changing concerning that particular theme, and speculates on possible future scenarios. Topics range from architecture to design and to audiovisual experimentation. The accompanying images contribute to a polyphonic and polysemous vision of Italian artistic production.